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[Classification of progressive systemic scleroderma] | JoVE Visualize

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[Classification of progressive systemic scleroderma]

H Holzmann, S Sollberg, P Altmeyer

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete|May 1, 1987

View abstract on PubMed

Summary

A novel classification for progressive systemic scleroderma (PSS) is introduced, incorporating rare forms and distinguishing between inflammatory and non-inflammatory subtypes based on immunogenetic factors. This updated system enhances understanding and future research into PSS.

Area of Science:

Rheumatology
Immunology
Dermatology

Context:

Progressive systemic scleroderma (PSS) presents diverse clinical manifestations.
Existing classifications may not fully encompass all PSS subtypes or pathogenetic mechanisms.

Purpose:

To introduce a new, comprehensive classification system for progressive systemic scleroderma (PSS).
To integrate pathogenetic factors, including immunological and immunogenetic criteria, into PSS classification.
To differentiate between noninflammatory and inflammatory subtypes of PSS.

Summary:

The proposed classification includes frequent and rare forms of PSS.
It considers pathogenetic factors, specifically immunological phenomena.
Distinguishes between noninflammatory and inflammatory PSS subtypes based on etiological (immunogenetic) criteria.

Impact:

Provides a more nuanced understanding of PSS heterogeneity.
Facilitates more precise diagnosis and targeted treatment strategies.
Serves as a foundation for future research and classification refinement.

Other Physical Sciences

Complex Physical Systems

[classification Of Progressive Systemic Scleroderma]