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In vivo hemodynamic comparison of porcine and pericardial valves | JoVE Visualize

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In vivo hemodynamic comparison of porcine and pericardial valves

D M Cosgrove, B W Lytle, C C Gill

The Journal of Thoracic and Cardiovascular Surgery|March 1, 1985

View abstract on PubMed

Summary

The Carpentier-Edwards pericardial valve offers better hemodynamic performance in the aortic position compared to porcine valves. It is less obstructive, improving blood flow efficiency after aortic valve replacement.

Area of Science:

Cardiovascular Surgery
Biomedical Engineering
Prosthetic Heart Valves

Background:

Tissue heart valves aim to improve hemodynamic function.
The Carpentier-Edwards porcine valve is a standard bioprosthesis.
Newer designs like the bovine pericardial and SupraAnnular valves seek enhanced performance.

Purpose of the Study:

To compare the hemodynamic performance of three aortic valve prostheses.
Evaluate the Carpentier-Edwards porcine, SupraAnnular, and bovine pericardial valves.
Assess valve function in the aortic position.

Main Methods:

Intraoperative hemodynamic assessment in 100 patients undergoing aortic valve replacement.
Comparison of mean gradients, valve orifice areas, and performance indices.
Analysis of valve performance across different valve sizes and flow rates.

Main Results:

Mean gradient decreased with increasing valve size for standard and pericardial valves.
The 23 mm pericardial valve demonstrated larger orifice areas and lower gradients than the 23 mm SupraAnnular valve.
The SupraAnnular valve showed superior hemodynamics to the standard porcine valve.
The pericardial valve was less obstructive than both porcine valves in the aortic position.

Conclusions:

The Carpentier-Edwards pericardial valve is hemodynamically superior to standard porcine valves in the aortic position.
The SupraAnnular valve also shows hemodynamic advantages over the standard porcine valve.
Bovine pericardial valves represent an improvement in reducing obstruction for aortic valve replacement patients.

Biomedical Engineering

Computational Physiology

In Vivo Hemodynamic Comparison Of Porcine And Pericardial Valves